Tv pilot 20141/3/2023 ![]() Intraoperative mean arterial blood pressures were similar (85 vs 87 mm Hg mean difference 2, P = 0.86), and there were no differences in short-term recovery characteristics or hospital length of stay. There was also a significant difference in mean volatile anesthetic administration (minimum alveolar concentration): 0.98 vs 0.64 (mean difference -0.35, P < 0.001) and target propofol concentrations: 4.0 vs 3.1 μg/mL (mean difference -0.8, P = 0.004). The mean of the median BIS/SE values for each patient during the maintenance phase of anesthesia in the low and high groups was significantly different: 39 vs 48 (mean difference 8, P < 0.001). ![]() One hundred twenty-five patients were recruited. A composite end point of postoperative complications (pneumonia, myocardial infarction, stroke, pulmonary embolism, heart failure, and death) was determined at 1 year. ![]() Secondary end points were postanesthesia care unit length of stay and pain scores, quality of recovery score, hospital length of stay, postoperative complications, and death. The primary end point was mean BIS or SE. The aims of the study were to determine whether anesthetic depth targeting in a high-risk group was feasible and to document anesthetic doses and arterial blood pressures associated with "deep" and "light" general anesthesia.ĪSA physical status III and IV patients, aged ≥60 years, having surgery lasting ≥2 hours, with expected hospital stay ≥2 days, and receiving general anesthesia were randomly allocated to a Bispectral Index (BIS) or spectral entropy (SE) target of 35 ("low" group) or 50 ("high" group). We conducted a pilot study to assess the feasibility of performing a definitive randomized controlled trial. The association may be causal or an epiphenomenon due to increased anesthetic sensitivity in high-risk patients. ![]() Deep general anesthesia has been associated with increased mortality in 5 observational studies. ![]()
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |